15 Best Anime Duos That You Should Watching Update 06/2022

Best Anime Duos

To keep things going, many anime rely on great character dynamics. It’s unlikely that these shows would be as famous if it weren’t for these legendary pairings!

When two characters operate so well together, it’s tough not to think of them as a single entity in any anime series. Despite being part of a wider group, those two characters share a special kinship that is greater than anything they could have imagined.

There are some duos that have a particular je ne sais quoi that makes them perfect for each other, or at the very least perfect to play off of one other.

Rich Keller updated the article on January 22nd, 2021.

There’s a proverb that goes something like this: You need buddies. The term “frenemies” is also used in various anime. Whether they’re the show’s lead actors or a supporting cast member, the best duos support one another and work together when they’re up against an opponent. An excellent twosome is one that can’t be discussed without mentioning the other, and that’s a fairly good sign.

1. Sekkekkyu & Hakkekkyu (Cells At Work)

Sekkekkyu & Hakkekkyu (Cells At Work)

It is true that without white blood cells, red blood cells cannot function. A closer relationship exists between the two in Cells at Work, though. When it comes to erythrocytes and neutrophils, there’s a link that goes beyond the typical functions of the human body.

Prior to meeting, they had already formed a close friendship. Hakkekky saved Sekkekky when she was a child from a bacteria. When she arrived at work on her first day, she was able to locate him because there was a strong connection between them.

2. Sailor Moon & Sailor Venus (Sailor Moon)

Twin sisters would be a possibility if these two were more alike. Venus, the former commander of the Sailor Guardians, sometimes takes Usagi’s place because of their striking resemblance. In addition, Venus is willing to die for Sailor Moon if necessary.

Their chemistry on and off the battlefield is what sets them apart as a formidable team. There is a tendency for them to spend a lot of time together in the playground because they have many of the same interests.

3. Saitama & Genos (One-Punch Man)

Saitama & Genos (One-Punch Man)

The One-Punch Man (Saitama) enjoys being among other superheroes, even though he doesn’t require them to beat enemies. Genos, a student of Saitama’s, is one among them. Genos, a demon cyborg, is nearly as powerful as his tutor despite being a lesser being.

Satima likes this method. There are no other heroes aware of the mental anguish that comes with dealing only one punch to the gut. They are in awe of his abilities. While One-Punch Man’s skills are awe-inspiring to his protege Genos, the latter makes sure his mentor is aware of his admiration.

4. Hunk & Pidge (Voltron)

Hunk and Pidge, members of the Lion Force quintet, are inseparable. However, it does not appear as though you knew each of them individually. One of the most capable members of Voltron is Pidge. Hunk is a foodie. Quite a few.

They’re still a great comedy duo, no matter what version of Voltron it is. So much so that their pranks occasionally get them in hot water. Even if things go bad, the two of them will be there for one other and support each other

5. Maka & Soul (Soul Eater)

This Soul Eater duo’s success may be difficult to discern. It doesn’t make sense that one can transform into a scythe while the other is just a normal girl. In spite of this, the two operate well together.

In most cases, the lack of romantic tension between them is to blame for it. There is no resemblance to Ross and Rachel. One of their primary aims is to take on evil’s powers. In some cases, it may take some time for them to get to know one other. They eventually understand one other’s desires and make them a reality.

6. Kagome & Inuyasha (Inuyasha)

Kagome & Inuyasha (Inuyasha)

It’s impossible not to respect Kagome’s tenacity or fall in love with Inuyasha’s grumpiness with these two characters. Inuyasha and Kagome form a formidable partnership.

A lot is learned about each other through their strong friendship, which makes for a fascinating series. Traveling together exposes them to people, places, and things they never would have encountered on their own.

7. Natsu & Happy (Fairy Tail)

Natsu and Happy’s story has a tragic backstory. Happy and the other Exceeds were each given the responsibility of defeating the Dragon Slayers, despite the fact that he doesn’t remember any of it. They became the best of friends and grew up together in Fairy Tail’s ranks, even though he had lost his memories.

8. Goku & Vegeta (Dragon Ball)

Son Goku and Vegeta’s love-hate relationship is one of the best in anime history. The two of them have been through a lot together: murder attempts, betrayals, kidnapping, and more. But they’ve always stuck by each other through it all.

The two Saiyans were so powerful because of their intense rivalry, which made them work more than normal to keep up with each other. There is something amusing about the fact that Trunks and Gotten, their two boys, are best buddies.

9. Sora & Shiro (No Game No Life)

Sora & Shiro (No Game No Life)

Even though Shiro and Sora’s relationship is far from perfect, this duo had to be included because of how well they work together.

Shiro is an 11-year-old prodigy who has a hard time expressing her feelings, whereas Sora is an 18-year-old boy who has a history of manipulating and destroying people. They have a way of making each other better. Because of their shared interest in video games, they were able to meet and form a lasting friendship.

10. Edward & Alphonse (Fullmetal Alchemist)

Edward and Alphonse had a deep and powerful connection that went beyond their ties as brothers. They’ve been through hell and back together and have become close as a result of the hardships they endured as children.

Those two had the kind of sibling bond that anyone would cherish. When they don’t get along, they argue and argue back. There’s no limit to what they’d do for each other and for their dream to become a reality.

11. Kageyama & Hinata (Haikyuu!!)

It was immediately clear that these two would make a formidable team from the moment they first appeared on television. With the exception of their shared passion for volleyball and their irrational stubbornness, they are polar opposites.

That, it turned out, was all they needed to come to terms on. However, despite their constant bickering, they are teammates and will always support each other.

12. Mustang & Hawkeye (Fullmetal Alchemist)

Mustang & Hawkeye (Fullmetal Alchemist)

This couple doesn’t seem like a good fit because their personalities are so different, yet they actually have a lot in common. Both of them are fierce and strong, and they both have great personalities as a result of their shared experiences. When they work together, they can’t be stopped.

Although neither one of them is very proficient at expressing their emotions, their relationship was precisely what they were looking for. They elevated trust to a new level, relying on one other to keep them on the right track. Without ever forgetting what drew them together in the first place, they encourage each other to move forward.

13. Isaac & Miria (Baccano!)

It’s impossible not to laugh at something that happens between these two. When it comes to partners in crime, Isaac and Miria are the finest of the best.

Despite the gloomy setting and the presence of the Sword of Damocles, these two characters offer a much-needed dose of lightheartedness and fun to the narrative. They’re not the most intelligent of the group, but their friendship is unbreakable. At the end of the day, it is all that matters.

14. Light & L (Death Note)

There’s a lot to like about these two, despite the fact that they’re a little out there in terms of popularity.

Although they are fighting for similar causes, L and Light have quite different ends in mind when they join forces. Their story brought them together despite the fact that they didn’t know each other, and there has never been a better team.

Both of these characters are eminently likable and intelligent individuals. Their determination to achieve their aims and prove who is the smarter one.. It’s all they need to keep coming up with fresh and creative methods to beat one other.

15. Gon & Killua (Hunter X Hunter)

Gon & Killua (Hunter X Hunter)

No one should be surprised by the fact that this outstanding combination took the top spot. Gon and Killua’s unique bond captivated the hearts of everyone who saw Hunter x Hunter.

Killua was bred and nurtured to be an assassin, doomed to a life of isolation. His chance encounter with Gon, who was bouncy, naive, and pure in heart, had a profound effect on him. Despite their differences, these two will always find a way back to each other and will go to great measures to protect each other, even if they don’t always agree.