20 Anime Guy And Girl Best Friends That You Should Watching Update 05/2024

It is possible for men and women to be friends. It’s true, however, that connections like these tend to have a will-they-or-won’t-they character. The friendship will be sacrificed in favor of some hot, passionate sex, whether it’s the result of one too many drinks, a tragic event, or a simple moment of weakness.

No, not with these people. We specifically sought out anime series in which a boy and a girl are just platonic friends. “Yeah, right,” you may be thinking. These stories show that boys and girls, men and women, can be friends and only friends.

This group of friends has each other’s backs through thick and thin with no sexual intent…for the most part, in the face of adversity (wink, wink). Steamy manga and friendship anime where two friends become lovers are immensely popular, but strictly platonic friendship anime is a popular genre of its own; perhaps because so many of us have tried and failed at being friends.

You’ll find real, deep friendships and relationships in these works, ones that stick with the protagonists through thick and thin. Eventually, you find yourself cheering for their friendship to endure and not end after a drunken booty call. We culled the best boy/girl best friend anime series out there, and here they are, in no particular order.

1. Absolute Duo

Absolute Duo

A fight at the Kouryou Academy’s opening ceremony paves the way for Tooru and Julie to become friends. Blazers, who can help students “materialize weaponry,” are what Tooru aspires to become in his quest for Absolute Duo strength. It turns out that Tooru’s special ability is actually a shield. It’s time for him to find out who killed his sister with the help of Julie, his new best friend/enemy.

2. No Game No Life

The boy and girl best friends in No Game No Life are actually two siblings. The main protagonists, Sora and Shiro, are legends in the realm of online gaming in this anime series, which is set in that universe. Then one day, they find themselves ensnared in an online chess competition. They quickly discover that the stakes in this game are enormous – on the order of the fate of the entire world! In the end, neither of these renowned gamers cares about rescuing the world; they simply want to win so that they can dominate the universe!

3. Magi

There are just two main characters in this show, yet the most of the story revolves on them, as well as their housegirl. Aladdin and his two friends, Alibaba and Morgiana, each confront their own hardships back home in their respective lands and kingdoms in this long-running drama. As they travel, they improve their magical abilities just in time for the impending “great war” that will annihilate everything they’ve worked for so far.

4. Ergo Proxy

Ergo Proxy

Ergo Proxy is a story with all the right ingredients. There is one place on Earth where human life persists after a catastrophic event has wiped out most of the civilization. Everyone in this future planet has a robot aide that resembles a human. While Re-I and Iggy work together, Vincent Law joins them after a virus causes the robots to become self-aware at the same time that supernatural phenomena begin to occur everywhere.

5. Planetes

The “Toy Box” (essentially a space dump truck) that Planetes uses to clear hazardous space trash floating between the Earth and the Moon is manned by three boys and a girl named “Space Buddies.” A human colony and corporate flags have been planted on the moon 50 years in the future. It’s as though the space grunts Ai, Hachirouta, and Philippe form an unlikely friendship as they embrace their ostracized job and take delight in it.

6. Ano Hi Mita Hana no Namae wo Bokutachi wa Mada Shiranai

In Ano Hi Mita Hana no Namae wo Bokutachi wa Mada Shiranai, Jinta’s best buddy returns from the grave. The first person to see Meiko (the ghost girl) is her best friend, who believes he is seeing things. Her spirit is restless, and he soon realizes that she has returned to him. In the company of their other childhood friends, they help Meiko find peace and finally rest – both of their spirits!

7. Steins;Gate


Banana-based green slime may not sound like much, but what if it could allow you to communicate via email into the past? In Steins;Gate, Rintarou and his pals Mayuri, Hashida, and Daru learn this lesson firsthand. What will they do with this newfound ability to travel back in time?

8. Kekkaishi

In the anime series Kekkaishi, only Kekkaishi posses supernatural powers that allow them to kill demons. Demons known as Ayakashi enter Yoshimura’s homeland in order to eat the power that exists in the area; they actually want to take control of it. To help Yoshimura fight these demons and save their world, he has the assistance of his childhood friend Tokine, a fierce Kekkaishi.

9. Machine-Doll wa Kizutsukanai

In Kikou Shoujo (Machine-Doll) wa Kizutsukanai, intelligent robots are given lifelike features, including the ability to reason and think for themselves. Raishin and Yaya face off against the best students at the Royal Academy while training to become the “Wiseman” in order to make up for his poor performance in his entrance exams. To gain the title of Wiseman and study the “forbidden” Machinarts, he ends up saving his opponents, but he has to come up with a novel means of doing it.

10. Rakudai Kishi no Cavalry

Rakudai Kishi no Cavalry

Similar blazers are used by the Rakudai Kishi no Cavalry. Ikki (the worst student at Hagun Academy) is challenged by Stella (the best Blazer) to a duel in this anime series, and the two become roommates. If one of you loses, you’ll be forced to serve the other as a slave.

11. Robotics;Notes

Aside from that, the two are childhood friends who are working on a massive robot as part of a club. The robotics club has tried for several years to improve the robot but has failed. Kai, on the other hand, could care less about Aki’s plans until he receives an odd letter that baffles him. Then he becomes serious and works with Aki to figure out what all this implies..

12. Shinsekai yori

When five children (Saki, Satoru, Shun, Maria and Mamoru) wake up in a world devastated by a virus that gave men the ability to manipulate matter and given others great psychic skills, they discover a society that has been turned into a dystopia. After the psychics build a new realm apart from the rest of the earth, peace and a new paradise can be achieved… but is this really the case?

13. Isshuukan Friends

Isshuukan Friends

After only a few days in Isshuukan Friends, Yuuki’s crush, Kaori, forgets about him. Yuuki continues to reintroduce himself to Kaori in the hopes of establishing a friendship with the cold and aloof girl, who has shown little interest in him. As time goes on, he discovers that she’s keeping her distance from him out of concern for the people she cares about. In contrast, Yuuki has no intention of giving up!

14. Nagi no Asukara

Underwater and surface dwellers populate Nagi no Asukara (A Lull in the Sea), a Japanese manga series. They are Hikari, Chisaki, Manaka and Kaname; they live underwater and attend a school on the surface, where they become friends with a surface-dweller. He has a soft spot for the ocean, despite the fact that prejudice and hatred have kept him and the people he admires apart.

15. Kiznaiver

Katsuhira and Chidori, childhood friends in Kiznaiver, are treated as if they were lab rats when they are taken and confined to the Kizuma System. As part of the system, they are placed in a group with four other kids who share their plight. If one person is in agony, everyone else will be in pain as well. Because Katsuhira does not feel any bodily or mental anguish, there is an issue

16. Bakuman


When Akito, the writer, asks Moritaka about helping him to create the best manga series in Japan’s history, they become more than students; they become best friends. For a while, Moritaka declines the offer, but then he gets the bright idea that he can land the girl of his dreams by asking her to join the cast as the show’s voice actor. This is the beginning of a close working relationship between the two Bakuman artists.

17. Orange

Naho’s present existence takes on a whole new significance when she receives a letter from her 26-year-old self. Her future in Orange is in jeopardy because of this letter, which attempts to help her avoid making the same mistakes again. She’s warned in a message from the future to keep an eye out for a new pupil named Kakeru, whose life may be in her hands depending on her actions today.

18. Hachimitsu to Clover

With Honey and Clover, five college pals experience love as they transition into adulthood in a true coming-of-age story. Even though Yuuta, Takumi, Shinobu, Hagumi, and Ayumi go through a lot of ups and downs, their relationship remains strong long after they all go their own ways.

19. One Piece

One Piece

To become Pirate King in One Piece, Luffy does not begin with a group of companions. Pirates around the world are on the lookout for the elusive “One Piece,” which will bring them great wealth and notoriety. Aside from being in it for the fun, he and his crew work together to help Luffy become Pirate King by locating the One Piece. They all become his buddies and partners in the quest.

20. Natsume Yuujinchou

The once friendless Natsume is haunted by angry restless spirits who have been bound in a book by his dead grandmother after she put them under her control in Natsume Yuujinchou (Natsume’s Book of Friends). In order to free the ghosts and open him to true friendship, he uses the Book of Friends to give them back their names.